Non-Invasive Pre-Implantation Genetic Testing in Hyderabad
Advancements in reproductive genetics have Advances in reproductive genetics have introduced additional approaches to embryo screening. At Fertilica IVF, we offer advanced Non-Invasive Pre-Implantation Genetic Testing (niPGT) in Hyderabad to helpassess cell-free DNA from embryo culture medium for information about chromosomal status without the need for embryo biopsy. By analyzing genetic material naturally released by embryos into the culture medium, niPGT provides valuable insights into embryo health while without performing a conventional embryo biopsy; the test’s limitations should be discussed with the treating specialist. This innovative approach can support better embryo selection, provide additional information that may support embryo-selection discussions, and help couples move closer to achieving a healthy pregnancy.
What is Non-Invasive Pre-Implantation Genetic Testing (niPGT)?
Non-Invasive Pre-Implantation Genetic Testing (niPGT) is an investigational approach to embryo genetic screening that analyses cell-free DNA collected from the culture medium surrounding a developing embryo during an IVF cycle.
Unlike conventional embryo-biopsy-based testing, niPGT aims to obtain genetic information without removing a sample of cells directly from the embryo. However, the accuracy and clinical usefulness of results can vary, and the findings may not fully reflect an embryo’s chromosomal status.
Potential benefits of niPGT include:
- Non-invasive embryo assessment
- No embryo biopsy procedure
- Reduced manipulation of embryos
- Improved embryo selection during IVF
- The clinical significance of niPGT results and their limitations should be discussed with a fertility specialist.
- Enhanced decision-making during embryo transfer
How Does Non-Invasive Pre-Implantation Genetic Testing (niPGT) Work?
The proposed process involves collecting the culture medium surrounding a developing embryo, analysing the DNA present in the sample, and interpreting the results using laboratory testing methods. The reliability of the result depends on factors such as sample quality, potential DNA contamination, laboratory methods, and the limitations of the testing approach. Results should not be interpreted as a guarantee of embryo health, implantation, pregnancy, or live birth.
Step 1
Fertility Evaluation and Treatment Planning
A comprehensive fertility assessment is conducted to determine whether niPGT is suitable for the patient's IVF cycle.
Step 2
Ovarian Stimulation
Fertility medications stimulate the ovaries to produce multiple mature eggs for retrieval.
Step 3
Egg Retrieval and Fertilization
Retrieved eggs are fertilized using IVF or ICSI techniques in a specialized embryology laboratory.
Step 4
Blastocyst Development
Embryos are cultured for several days until they reach the blastocyst stage.
Step 1
Collection of Culture Medium
Instead of performing an embryo biopsy, embryologists collect the spent culture medium surrounding the developing embryo.
Step 2
Cell-Free DNA Analysis
Genetic material released by the embryo into the culture medium is isolated and prepared for testing.
Step 3
Chromosomal Screening
Advanced genetic testing technologies analyze the DNA for chromosomal abnormalities and aneuploidy.
Step 4
Genetic Interpretation
Embryos are categorized based on their genetic screening results to support embryo selection.
Step 1
Genetic Counselling
Results are reviewed with the couple and integrated into the overall IVF treatment plan.
Step 2
Selection of Preferred Embryos
Embryos showing favorable genetic profiles may be prioritized for transfer.
Step 3
Frozen or Fresh Embryo Transfer
Depending on the treatment protocol, selected embryos are transferred during an appropriate cycle.
Step 4
Pregnancy Monitoring
Pregnancy testing and ongoing follow-up care are provided after embryo transfer.
Understanding the Limitations of Non-Invasive Pre-Implantation Genetic Testing (niPGT)
Non-invasive preimplantation genetic testing is an evolving area of reproductive research. Published evidence has identified limitations in diagnostic accuracy and consistency, and clinical benefits have not been conclusively established.
Before considering any embryo genetic testing approach, patients should receive clear information about the evidence, limitations, alternatives, and potential implications of the results. The appropriate approach should be discussed with a qualified fertility specialist in accordance with current professional guidance.
| Patient Age | Success Rate | Notes |
|---|---|---|
| Under 30 Years | 60% – 75% | High proportion of chromosomally normal embryos |
| 30 – 34 Years | 55% – 70% | Strong implantation and pregnancy potential |
| 35 – 37 Years | 45% – 60% | niPGT may assist embryo selection |
| 38 – 40 Years | 35% – 50% | Increased chromosomal abnormalities may affect outcomes |
| Above 40 Years | 20% – 35% | Success largely depends on embryo quality and ovarian reserve |
Non-Invasive Pre-Implantation Genetic Testing (niPGT) Cost in Hyderabad
At Fertilica IVF, we are committed to offering advanced fertility technologies with complete transparency. The cost of niPGT in Hyderabad depends on factors such as the IVF cycle, number of embryos analyzed, genetic testing technology used, and laboratory requirements.
Before beginning treatment, our fertility specialists provide a comprehensive cost estimate to ensure complete clarity and confidence throughout the treatment journey.
Factors Affecting Non-Invasive Pre-Implantation Genetic Testing (niPGT) Cost in Hyderabad?
- Fertility consultation and assessment
- IVF or ICSI treatment costs
- Ovarian stimulation medications
- Number of embryos available for testing
- Genetic laboratory analysis fees
- Embryo culture and monitoring charges
- Embryo freezing and storage costs
- Frozen embryo transfer (FET) expenses
- Genetic counselling services
- Additional fertility treatments if required
Non-Invasive Pre-Implantation Genetic Testing (niPGT) Cost Comparison in India & Worldwide
| Country | Approximate Cost |
|---|---|
| India | ₹2,50,000 – ₹5,50,000 |
| USA | $12,000 – $25,000 |
| UK | £7,000 – £15,000 |
| UAE | AED 25,000 – AED 55,000 |
| Singapore | SGD 10,000 – SGD 22,000 |
| City | Approximate Cost |
|---|---|
| Hyderabad | ₹2,50,000 – ₹5,50,000 |
| Bangalore | ₹3,00,000 – ₹6,00,000 |
| Chennai | ₹2,75,000 – ₹5,75,000 |
| Mumbai | ₹3,50,000 – ₹7,00,000 |
| Delhi | ₹3,25,000 – ₹6,50,000 |
Why Choose Fertilica IVF for Non-Invasive Pre-Implantation Genetic Testing (niPGT) Clinic in Hyderabad?
At Fertilica IVF, we offer advanced Non-Invasive Pre-Implantation Genetic Testing (niPGT) services to support embryo selection while minimizing intervention during the IVF process. Our experienced fertility specialists and embryologists utilize cutting-edge non-invasive embryo screening technology in state-of-the-art IVF and genetic laboratories to help, explain the test method without suggesting it reliably predicts implantation.for successful implantation. We provide personalized fertility treatment protocols tailored to each couple's reproductive needs, supported by comprehensive genetic counselling to help patients understand the testing process and make informed decisions. With transparent pricing, ethical treatment practices, advanced embryo culture and cryopreservation systems, and compassionate patient-centered care, we ensure a seamless fertility journey. Our niPGT services are Use specific, verifiable details about the laboratory, testing process, and counselling offered and reproductive genetics programs, enabling couples to benefit from the latest innovations in assisted reproductive technology.
Consultation and Individualized Fertility Care
Fertility treatment decisions depend on each patient's reproductive history, medical assessment, and treatment goals. A fertility specialist can explain available testing options, their limitations, and whether an approach is appropriate under current clinical guidance.
At Fertilica IVF, patients can seek a consultation to discuss their fertility evaluation and understand the options relevant to their individual circumstances.
How to Prepare for Non-Invasive Pre-Implantation Genetic Testing (niPGT) — Pre-Treatment Checklist
Proper preparation before undergoing Non-Invasive Pre-Implantation Genetic Testing (niPGT) can help optimize treatment outcomes and support informed embryo selection. At Fertilica IVF, our specialists provide personalized guidance throughout the IVF and niPGT journey to ensure you are fully prepared for every stage of treatment.
Medical Preparation
Begin with a comprehensive fertility consultation and reproductive health evaluation. Your specialist may recommend hormonal blood tests, ultrasound assessments, and other diagnostic investigations to assess fertility potential and treatment readiness. If you have undergone IVF previously, your fertility history and past treatment outcomes will be carefully reviewed. Discussions regarding genetic screening options will help determine whether niPGT is appropriate for your individual circumstances.
Treatment Planning
Take time to understand the IVF and niPGT process, including ovarian stimulation, egg retrieval, embryo culture, genetic analysis, and embryo transfer planning. Your fertility specialist will explain expected treatment timelines, embryo development stages, and how niPGT results may be used to support embryo selection. Discussions regarding embryo freezing and future transfer plans are also an important part of treatment preparation.
Lifestyle Preparation
Maintain a healthy body weight and follow a balanced diet rich in essential nutrients that support reproductive health. Avoid smoking, alcohol consumption, and recreational substances, as these may negatively affect egg quality, sperm health, and embryo development. Follow all prescribed medications, vitamins, and fertility supplements exactly as directed by your fertility specialist.
Emotional & Financial Preparation
Ensure that you understand both the benefits and limitations of niPGT before beginning treatment. Review treatment costs, laboratory fees, and any potential embryo storage charges so you can plan accordingly. Consider counselling or emotional support services if needed, and build a strong support network of family members, friends, or your partner to help you navigate the treatment journey with confidence.
Proper preparation, advanced laboratory expertise, and individualized fertility care can help maximize the benefits of niPGT and support informed embryo selection for a successful pregnancy.
Frequently Asked Questions
Everything you need to know about Non-Invasive Pre-Implantation Genetic Testing at Fertilica
