Embryo Biopsy Technique in IVF

Embryo Biopsy Technique in IVF

Embryo Biopsy Technique in IVF

Embryo-Biopsy And Pre-Implantation Genetic Testing in Hyderabad

At Fertilica IVF, we recognize that every couple’s journey to parenthood is unique, and that informed decision‑making can transform outcomes. Embryo biopsy and Pre‐Implantation Genetic Testing (PGT) represent the cutting edge of assisted reproductive technology, allowing embryologists to assess chromosomal integrity and inherited genetic traits before embryo transfer. By integrating the embryo biopsy procedure into our IVF protocols, we enhance implantation success, minimize miscarriage risk, and help you welcome a healthy baby. As pioneers of Embryo‐Biopsy And Pre‐Implantation Genetic Testing Treatment in Hyderabad, Fertilica IVF combines sophisticated laboratory infrastructure with personalized patient care to deliver accurate, reliable results.

Embryo-Biopsy And Pre-Implantation Genetic Testing

Understanding the Embryo Biopsy Procedure

The embryo biopsy procedure is a minimally invasive technique performed on embryos at the appropriate developmental stage—typically on day three (cleavage stage) or day five (blastocyst stage) post-fertilization. During this process, a few cells are gently removed under high‑resolution microscopy, ensuring the embryo’s viability remains uncompromised. These cells are then sent for molecular analysis to detect aneuploidies (chromosomal abnormalities) or specific gene mutations. Advances in vitrification allow for immediate freezing of embryos post-biopsy, maintaining viability until results are available. This precise approach to embryo selection not only optimizes implantation rates but also reduces the emotional and financial burden of multiple IVF cycles.

The Importance of Pre‑Implantation Genetic Testing

Pre implantation Genetic Testing empowers couples with critical insights into their embryos’ genetic health before pregnancy begins. By screening for chromosomal aneuploidies (PGT‑A), single‑gene defects (PGT‑M), or structural rearrangements (PGT‑SR), clinicians can prioritize embryos with the highest potential for successful, healthy pregnancy. This strategic selection reduces the likelihood of miscarriage, eliminates the need for invasive prenatal diagnostics later on, and supports informed family planning—especially for those with known hereditary conditions. Fertilica IVF’s Pre‐Implantation Genetic Testing protocols adhere to international quality standards, ensuring accuracy and reproducibility when it matters most.

Types of Embryo Genetic Testing

  • PGT‑A (Aneuploidy Screening): Detects whole‑chromosome gains or losses in embryos, reducing miscarriage risk.
  • PGT‑M (Monogenic Disease Testing): Screens for specific inherited gene mutations carried by one or both partners.
  • PGT‑SR (Structural Rearrangement Testing): Identifies unbalanced chromosomal rearrangements that may compromise embryo development.

Diagnostic Tests & Procedures Related to PGT

A comprehensive understanding of Diagnostic Tests & Procedures Related to PGT is vital for couples considering genetic screening. Following embryo biopsy, extracted cells undergo DNA amplification, sequencing, and bioinformatic analysis to reveal chromosomal and gene‑level insights. Our diagnostic workflow includes sample handling protocols to avoid contamination, rapid turnaround times of 5–7 days, and secure reporting via our patient portal. We also offer genetic counseling before and after testing, ensuring you understand your results and their implications. This integrative approach—combining cutting‑edge laboratory processes with expert interpretation—maximizes the reliability of Pre‑Implantation Genetic Testing outcomes.

Who Can Benefit from Pre‑Implantation Genetic Testing?

Couples with a history of recurrent miscarriage, advanced maternal age (35+), previous IVF failures, or known genetic disorders are prime candidates for PGT. Additionally, those seeking gender selection for medical reasons or families with a history of single‑gene diseases (such as thalassemia or cystic fibrosis) may benefit from targeted embryo genetic testing. Fertilica IVF’s fertility specialists conduct thorough assessments—including carrier screening and karyotyping—to determine PGT eligibility. By aligning patient profiles with the appropriate Diagnostic Tests & Procedures Related to PGT, we craft bespoke treatment plans that address both medical and emotional considerations.

The IVF Cycle with Embryo Biopsy and PGT: Step by Step

An IVF cycle incorporating embryo biopsy and PGT involves several critical stages. First, ovarian stimulation stimulates multiple follicles, followed by ultrasound‑guided egg retrieval. Retrieved oocytes are fertilized via conventional IVF or ICSI (intracytoplasmic sperm injection) to ensure optimal fertilization rates. Embryos develop in culture until the day of biopsy—either day three or day five—when embryologists carefully remove a few cells for genetic analysis. Post‑biopsy, embryos are vitrified to preserve viability. Once PGT results are available, euploid embryos (those without detected abnormalities) are selected for transfer or future cycles. Throughout, our team monitors hormone levels, prepares the uterine lining, and provides personalized guidance to support your comfort and confidence.

  • Ovarian Stimulation: Stimulates multiple follicles with medications.
  • Egg Retrieval: Performed under ultrasound guidance.
  • Fertilization: Through IVF or ICSI.
  • Embryo Development: Cultured until day three or five for biopsy.
  • Biopsy: Carefully removes cells for analysis.
  • Vitrification: Freezes embryos until results are received.
  • Transfer: Transfers healthy embryos after results are available.

Success Rates and Advantages of PGT

Integrating PGT into IVF cycles has been shown to significantly improve implantation rates and live birth outcomes, particularly for patients with risk factors. By transferring only chromosomally normal embryos, the likelihood of early pregnancy loss decreases and time to pregnancy shortens. Numerous studies report clinical pregnancy rates above 60% per transfer when PGT is applied in appropriate candidates. Additionally, PGT reduces the emotional toll of repeated failed cycles and lowers healthcare costs over time. At Fertilica IVF, our transparent reporting and outcome tracking demonstrate the tangible benefits of embryo genetic testing, reinforcing our commitment to delivering the highest standard of fertility care.

Cost Considerations for Embryo‑Biopsy and PGT Treatment in Hyderabad

Cost is an important factor when considering Embryo‑Biopsy And Pre‑Implantation Genetic Testing Treatment in Hyderabad. Fertilica IVF provides detailed breakdowns covering ovarian stimulation medications, egg retrieval, embryology lab fees, embryo biopsy procedure, and genetic test analysis. While PGT adds to the baseline IVF investment, many patients find the improved success rates and reduced miscarriage risk justify the expense. We offer flexible payment plans, package discounts, and transparent counseling to help you make an informed decision. Our financial coordinators work closely with you to map out expected costs, ensuring clarity and peace of mind before embarking on your fertility journey.

Preparing for Your Embryo Biopsy and PGT Journey

Optimal preparation enhances PGT outcomes and patient comfort. Prior to treatment, we recommend pre‑cycle assessments—such as hormone profiling, ovarian reserve testing, and infectious disease screening—to tailor protocols. Lifestyle modifications, including nutritional optimization, smoking cessation, and stress management, can further improve egg quality and endometrial receptivity. During biopsies, mild sedation ensures patient comfort while maintaining embryo safety. Our multidisciplinary teams—fertility physicians, embryologists, genetic counselors, and nursing staff—coordinate seamlessly to deliver a supportive, patient‑centric experience from consultation through follow‑up.

Aftercare and Follow‑Up in Embryo Genetic Testing

Post‑transfer care is crucial for implantation and early pregnancy support. Fertilica IVF provides personalized luteal support regimens, incorporating progesterone supplements and monitoring hormonal levels. Following genetic diagnosis, our genetic counselors review PGT reports with you, explaining any findings and discussing implications for future family planning. We schedule timely ultrasounds to confirm implantation and fetal heartbeat, and remain available to address any questions or concerns. This continuum of care extends beyond the lab, ensuring that your embryo biopsy procedure and Pre‑Implantation Genetic Testing experience is supported by clinical excellence and empathetic guidance.

Your Path to a Healthy Pregnancy

Embryo biopsy procedure and Pre‑Implantation Genetic Testing represent transformative advances in reproductive medicine, offering hope and clarity for couples facing fertility challenges. At Fertilica IVF, our reputation as leaders in Embryo‑Biopsy And Pre‑Implantation Genetic Testing Treatment in Hyderabad reflects our dedication to scientific rigor, compassionate care, and personalized treatment planning. If you are considering embryo genetic testing or wish to learn more about Diagnostic Tests & Procedures Related to PGT, contact our Fertility Consultants today. Together, we will chart a path toward a healthy pregnancy and the joyful arrival of your child.

Frequently Asked Questions

1. What is embryo biopsy in IVF treatment?

Embryo biopsy is a procedure where a few cells are removed from a developing embryo (usually on day 5 or 6) to test for genetic or chromosomal abnormalities before implantation.

2. What is Pre-Implantation Genetic Testing (PGT)?

PGT is a genetic screening method performed on embryos to detect inherited disorders or chromosomal issues before transferring the embryo into the uterus.

3. Who should consider PGT during fertility treatment?

PGT is recommended for couples with a history of genetic disorders, recurrent pregnancy loss, advanced maternal age, or previous failed IVF cycles.

4. HOW IS PGT/EMBRYO BIOPSY DONE?

During PGT testing, a few cells from embryos outer shell are removed using a laser at specific stages of embryo development depending on the type of PGT being conducted and sent for genetic analysis.

5. Is embryo biopsy safe for the embryo?

Yes, when performed by experienced embryologists, embryo biopsy is generally safe and does not harm the embryo’s ability to implant and grow into a healthy pregnancy.

6. WHAT IS THE COST OF PGT?

The cost of PGT- Embryo biopsy is around 25,000 INR per embryo. It also depends on the type of PGT test performed. Talk to the fertility counsellor for detailed estimate.